Searchable abstracts of presentations at key conferences in endocrinology

ea0037gp.12.03 | Diabetes and obesity – Translational diabetes | ECE2015

Can physical activity modify the impact of the genes on the incidence of type 2 diabetes mellitus?

Szczerbinski Lukasz , Bauer Witold , Goscik Joanna , Wawrusiewicz-Kurylonek Natalia , Paczkowska Magdalena , Niemira Magdalena , Citko Anna , Ciborowski Michal , Maliszewska Katarzyna , Adamska Edyta , Kretowski Adam , Gorska Maria

The exact mechanism of the development of T2DM is still unclear, however, it is known that important role is played by both environmental and genetic factors. In this study we focused on describing the interactions between environmental and genetic factors and answering the question whether physical activity can modify the impact of the genes on the incidence of T2DM. We recruited 921 subjects (median age: 38 years; 49.7% man; mean BMI: 28.1) from the cohort 1000 Polish Longit...